Tandem mass spectrometry (MS-MS), mass analyzers, etc.
MS/MS (Tandem MS) comes in many different flavors (e.g. the “triple quadrupole (QqQ), Q-orbitrap (e.g. Q-Exactive), Q-Time of Flight (Q-TOF)), […]
What is metabolomics?
What is metabolomics? My definition: Identifying, measuring and tracking the small biochemical intermediates formed during the making, breaking, and interconversion between biochemical molecules to figure out what organisms are up to.
Mass resolution and mass accuracy in mass spectrometry
When it comes to mass spectrometry, don’t confuse high resolution and accurate mass! High resolution is basically having sharp spectral […]
Retention Indexes
Pay attention to Retention (Time)! In GC-MS (gas chromatography-mass spectrometry) or LC-MS (liquid chromatography-mass spectrometry), chromatography has two main benefits […]
Chromatography-coupled mass spectrometry graph types, etc.
Chromatography-paired mass spectrometry typically uses mass spectrometry (MS), coupled to liquid chromatography (LC) or gas chromatography (GC) to aid in […]
Derivatization of metabolites for GC-MS via methoximation+silylation
Silylation may sound silly to say, but if you want to make organic acids volatile for GC-MS, it gives you […]
