Cryo-electron microscopy (cryo-EM) & structural biology
Dying to know “What’s the deal with cryo?” Cryo-Electron Microscopy (CryoEM) has transformed the structural biology field in recent years, […]
Protein structure & Insulin – solving its structure and using it to treat diabetes
Solving the structure of insulin (figuring out the 3D arrangement of its atoms) was the crowning achievement for the pioneering […]
X-ray crystallography helps us pretty protein “see”
We’ve been “looking” a lot at proteins, the main workhorses of our cells, which do everything from provide structural support […]
Site-directed mutagenesis
I voted to try to bring about political change, and I use site-directed mutagenesis to bring about protein change! With […]
Coronavirus protease inhibitors and the importance of structural biology
This is the SARS-CoV-2 main protease (MPro). SARS-CoV-2 is the novel coronavirus responsible for causing the pandemic disease Covid-19. This […]
GFP – what’s there to see?
Looking for some at-home activity you can do for free? How ‘bout building a paper model of GFP?! GFP stands […]
Dorothy Crowfoot Hodgkin – and how she made protein x-ray crystallography possible – and was just super awesome overall
Sometimes I can’t believe how awesome people are…Dorothy Crowfoot Hodgkin (May 12, 1910 – July 29, 1994) was a true […]
Penicillin, its structure-solving, and how β-lactam antibiotics work
How does penicillin do its bacteria killin’? And how did a couple superhero female crystallographers help us harness its power […]
Resolution – in x-ray crystallography vs digital screens
Why is 8K screen resolution better than 4K, but an 8Å x-ray crystallography structure is worse than a 4Å one? […]
X-ray crystallography
What will 2020 bring? I don’t have a crystal ball, but I do have protein crystals! And I predict that, […]
