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The Bumbling Biochemist

The Bumbling Biochemist

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Category: amino acids

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Arginine, basic vs. acidic amino acids

December 15, 2020December 21, 2025

Arguing about arginine? And what “basicity” means? Today I want to introduce you to the last of the “basic” amino […]

Histidine, immobilized metal affinity chromatography

December 14, 2020March 23, 2026

Today I His-tagged my His-smas tree… HISTIDINE (His, H) may be an amino *acid* but it can also be a […]

Lysine, Schiff bases

December 12, 2020December 31, 2024

Move over Kelloggs, this “K” is way more special than your cereal! Why? For one, the amino acid (protein letter) […]

Cysteine – disulfide bonds, reducing agents, perms

December 11, 2020December 12, 2024

The Sistine Chapel wasn’t built in a day, but thanks to the amino acid cysteine (Cys, C) your hair can be […]

Proline – hydrogen bonding, bond angles, collagen

December 10, 2020December 16, 2025

What’s a side chain that’s curvy gotta do with scurvy? Proline isn’t *pro*-lines & it’s definitely *anti* α-helix!  But it’s […]

Tryptophan, serotonin, melatonin, spectroscopy, etc.

December 9, 2020December 9, 2024

What’s Tweety bird’s fave amino acid?  tWiptophan! Tryptophan (Trp) is abbreviated W & you can remember this by saying it […]

Isoleucine, Maple Syrup Urine Disease

December 5, 2020August 13, 2025

Who doesn’t love the smell of maple syrup? Doctors who smell it coming from diapers! Don’t know what I’m talking […]

Leucine, ketogenic amino acids

December 4, 2020November 24, 2024

No losers here – just LEUCINE! Lighten up! But stay lucid!  today I’m elucidating the amino acid Leucine (Leu, L) […]

Valine, branched-chain amino acid breakdown

December 3, 2020November 24, 2024

I know it’s not tis *that* season, but would you be my Valine-tine? Today in #20DaysOfAminoAcids, another protein letter to […]

Glycine and early protein chemistry research

December 1, 2020December 1, 2024

Today I’m kicking off the 2020 bumbling biochemist’s version of an advent calendar – #20DaysOfAminoAcids – with the “opening up” […]

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