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tiny beads with superpowers! Often they have a sugar (such as agarose or dextrose) or polyacrylamide core that’s been “functionalized” with the addition of chemical groups that give them particular properties such as a + or – charge. Resin can be packed into chromatography columns and used to separate proteins based on how they interact with it. You can use different resins with different superpowers to separate proteins based on different properties.